5. Rudolf-Höfer-Prize awarded

Gruppenbild (© Stefan Burghart)

© Stefan Burghart

Vienna – On April 9th, the 5th Rudolf-Höfer-Prize for the best publication in conjunction with the application of radioactive isotopes in clinics and research in Austria was awarded to the honour of Univ.-Prof. Dr. Rudolf Höfer in the Billrothhaus. Under the honorary patronage of Univ.-Prof. Dr. Rudolf Höfer, founder and pioneer of nuclear medicine in Austria the top three publications of all submitted contributions were presented. The evening was moderated by the members of the jury, Univ.-Prof. Dr. Michael Krainer (Dept. for Oncology, Univ.-Clinic for Internal Medicine I, MedUni Wien) and Univ.-Prof. Dr. Kurt Derfler (Institute ATHOS, Vienna) together with the head of the jury, Univ.-Prof. Dr. Helmut Sinzinger (Institute ATHOS, Wien). The award was sponsored by DSD Pharma GesmbH.

After a short introduction to the impressive lifetime achievement of Prof. Dr. Höfer, the submitted publications were presented by the selected candidates. The session was opened by Dr. Marie Spies (publication „Brain Monoamine Oxidase A in Seasonal Affective Disorder and Treatment with Bright Light Therapy“). Thereafter the paper „Spatial analysis and high resolution mapping of the human whole-brain transcriptome for integrative analysis in neuroimaging“ was presented by Dr. Gregor Gryglewski. The session was closed by Maximilian Klingler,PhD with the contibution „DOTA-MGS5, a new cholecystokinin-2 receptor targeting peptide analog with optimized targeting profile for theranostic use – Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting”.

After the lecture the three selected presentations were evaluated by the jury. First place was awarded to Dr. Gregor Gryglewski for his publication „Spatial analysis and high resolution mapping of the human whole-brain transcriptome for integrative analysis in neuroimaging“. Gene transcription in RNA is mandatory for the synthesis of proteins which trigger the cell function. A method was presented by which the expression of RNA of any gene in the whole human brain could be predicted from transcriptional data from a database. By the help of proton emission tomography (PET) it could be shown that the predicted RNA expression is corellated with the measured distribution of proteins. Public available transcriptional data of the whole brain allow an assessment of the correllation of specific genes with pathological processes and may enable the development of new therapeutic or diagnostic processes now.

www.meduniwien.ac.at/neuroimaging/mRNA.html, https://doi.org/10.1016/j.neuroimage.2018.04.068

The Society of Doctors in Vienna congratulates all award winners for the numerous applications as well as their outstanding contributions. Special thanks to the Sponsor DSD Pharma GesmbH and Managing Director Dr. Susanne Dorudi who presented the Rudolf-Höfer-Prize for this year.

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